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Eun-Joo Shin Selected Research

Dextromethorphan (Racemethorphan)

12/2021Ouabain inhibitor rostafuroxin attenuates dextromethorphan-induced manic potential.
10/2010Neuropsychopharmacological understanding for therapeutic application of morphinans.
1/2008Neuropsychotoxicity of abused drugs: potential of dextromethorphan and novel neuroprotective analogs of dextromethorphan with improved safety profiles in terms of abuse and neuroprotective effects.
12/20063-Hydroxymorphinan, a metabolite of dextromethorphan, protects nigrostriatal pathway against MPTP-elicited damage both in vivo and in vitro.
4/2005The dextromethorphan analog dimemorfan attenuates kainate-induced seizures via sigma1 receptor activation: comparison with the effects of dextromethorphan.
5/2004Dimemorfan prevents seizures induced by the L-type calcium channel activator BAY k-8644 in mice.
1/2003Metabolism to dextrorphan is not essential for dextromethorphan's anticonvulsant activity against kainate in mice.

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Eun-Joo Shin Research Topics

Disease

15Mitochondrial Diseases (Mitochondrial Disease)
07/2021 - 01/2009
14Cognitive Dysfunction
01/2022 - 12/2005
14Seizures (Absence Seizure)
01/2021 - 12/2002
7Parkinson Disease (Parkinson's Disease)
07/2021 - 12/2006
7Neuroinflammatory Diseases
01/2021 - 01/2009
6Alzheimer Disease (Alzheimer's Disease)
02/2021 - 09/2005
6Schizophrenia (Dementia Praecox)
02/2021 - 12/2005
6Neurodegenerative Diseases (Neurodegenerative Disease)
02/2021 - 11/2008
4Hyperthermia
08/2021 - 01/2015
4Memory Disorders (Memory Loss)
01/2021 - 12/2004
4Substance-Related Disorders (Drug Abuse)
11/2020 - 01/2008
3Mania (Manias)
12/2021 - 01/2020
3Psychotic Disorders (Schizoaffective Disorder)
04/2017 - 01/2010
3Neuroblastoma
08/2015 - 01/2012
3Inflammation (Inflammations)
06/2012 - 11/2008
3Epilepsy (Aura)
08/2011 - 05/2008
2Serotonin Syndrome (Syndrome, Serotonin)
07/2021 - 01/2019
2Brain Ischemia (Cerebral Ischemia)
02/2021 - 11/2020
2Amyloid Plaque
08/2015 - 01/2012
1Suppuration
02/2022
1Chronic Renal Insufficiency
01/2022
1Neoplasms (Cancer)
01/2022
1Bipolar Disorder (Manic Depressive Psychosis)
02/2021
1Reperfusion Injury
11/2020
1Necrosis
04/2016

Drug/Important Bio-Agent (IBA)

10Proteins (Proteins, Gene)FDA Link
11/2020 - 05/2004
9Methamphetamine (Desoxyn)FDA LinkGeneric
07/2021 - 12/2009
9Kainic Acid (Kainate)IBA
01/2021 - 01/2003
7Dextromethorphan (Racemethorphan)FDA LinkGeneric
12/2021 - 01/2003
7Glutathione (Reduced Glutathione)IBA
01/2021 - 09/2011
7Phencyclidine (Angel Dust)IBA
11/2018 - 05/2004
6AntioxidantsIBA
01/2019 - 01/2004
5Cocaine (Cocaine HCl)IBA
11/2020 - 04/2016
4ginsenoside ReIBA
07/2021 - 06/2014
4Cholinergic Agents (Cholinergics)IBA
01/2019 - 06/2013
4Neuroprotective AgentsIBA
06/2012 - 12/2006
3DNA (Deoxyribonucleic Acid)IBA
08/2021 - 01/2004
3Glutathione PeroxidaseIBA
07/2021 - 05/2008
3NADPH Oxidases (NAD(P)H oxidase)IBA
11/2018 - 01/2016
3Protein Kinases (Protein Kinase)IBA
01/2018 - 06/2014
3trimethyltinIBA
11/2017 - 08/2011
3Naloxone (Narcan)FDA LinkGeneric
10/2016 - 09/2009
3N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
08/2015 - 12/2005
3Reactive Oxygen Species (Oxygen Radicals)IBA
07/2015 - 09/2011
3Growth Hormone (Somatotropin)IBA
09/2014 - 09/2005
2Dopamine (Intropin)FDA LinkGeneric
08/2021 - 04/2017
2Serotonin (5 Hydroxytryptamine)IBA
07/2021 - 01/2019
25-HT2A Serotonin Receptor (5 HT2A Receptor)IBA
07/2021 - 07/2009
2Pharmaceutical PreparationsIBA
02/2021 - 03/2014
2SeleniumIBA
02/2021 - 12/2020
2Superoxide DismutaseIBA
02/2020 - 05/2008
2LithiumIBA
02/2020 - 01/2020
2Dextroamphetamine (Dexedrine)FDA LinkGeneric
02/2020 - 01/2020
2Janus Kinase 2IBA
01/2019 - 11/2017
24- ethoxymethylene- 2- phenyl- 2- oxazoline- 5- one (phOx)IBA
11/2018 - 01/2016
2Clozapine (Clozaril)FDA LinkGeneric
11/2018 - 05/2018
2Antipsychotic Agents (Antipsychotics)IBA
05/2018 - 12/2005
2DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA
01/2018 - 08/2015
2prolinedithiocarbamate (PDTC)IBA
01/2018 - 05/2004
2Interleukin-6 (Interleukin 6)IBA
11/2017 - 06/2013
2Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
11/2017 - 06/2013
2Caspase 3 (Caspase-3)IBA
04/2016 - 08/2015
2Amyloid (Amyloid Fibrils)IBA
09/2015 - 08/2015
2gintoninIBA
09/2015 - 01/2012
2nobiletinIBA
08/2015 - 08/2013
2FlavonoidsIBA
08/2015 - 08/2013
21- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA
06/2012 - 12/2006
2Arachidonic Acid (Vitamin F)IBA
09/2011 - 08/2011
2LipopolysaccharidesIBA
01/2010 - 12/2006
2GinsenosidesIBA
02/2009 - 01/2009
2Malondialdehyde (Propanedial)IBA
05/2008 - 05/2004
2dimemorfan (AT 17)IBA
04/2005 - 05/2004
2DextrorphanIBA
05/2004 - 01/2003
1Polyurethanes (Polyurethane)IBA
02/2022
1Angiotensin IIIBA
01/2022
1NVP-BKM120IBA
01/2022
1Phosphatidylinositols (Phosphatidylinositol)IBA
01/2022
1EnzymesIBA
02/2021
1Neurotransmitter Agents (Neurotransmitter)IBA
02/2021
1Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA
01/2021
1Valproic Acid (Depakote)FDA LinkGeneric
02/2020
1Adenosine Monophosphate (AMP)IBA
01/2020
1theanineIBA
01/2019
1Cholinergic ReceptorsIBA
01/2019
1Dopamine D1 Receptors (Dopamine D1 Receptor)IBA
01/2019
15-Hydroxytryptophan (5 Hydroxytryptophan)IBA
01/2019
12- (4- morpholinyl)- 8- phenyl- 4H- 1- benzopyran- 4- oneIBA
11/2018
1Trichloroethylene (Trichloroethene)IBA
07/2018
1src-Family KinasesIBA
05/2018
1Platelet Activating FactorIBA
01/2018
1LipidsIBA
01/2018
1Glutamic Acid (Glutamate)FDA Link
04/2017
1Polymethyl Methacrylate (Sol)IBA
11/2016
1Dizocilpine Maleate (Dizocilpine)IBA
10/2016
1rottlerinIBA
04/2016
1Scopolamine (Hyoscine)FDA Link
09/2015
1Cytochromes c (Cytochrome c)IBA
08/2015
1flavoneIBA
08/2015

Therapy/Procedure

2Oral Administration
09/2015 - 01/2012
1Self Administration (Administration, Self)
01/2019